The flow and structure of an application design for unmanned aerial vehicles (UAVs) are examined in this research. We also show an example of modeling and simulation study with the ANSYS Fluent and Mechanical programs. This research reveals the unmanned aerial vehicle’s structural and mechanical design, structure configurations, energy-flow and structural analysis, propulsion and firing systems, prototype production and testing, and design flow models. This study aims to complete the unmanned aerial vehicle design by determining its aerodynamic configurations. Due to the complexity of the design, a preliminary preparation for flow analysis is performed with simplified geometry as well as flow analysis. The unmanned aerial vehicle is tested at different velocities by numerical analysis. In addition, different density flow analyses provide predictions about the aerodynamic forces of the UAVs at different heights and temperatures. The thrust results are 4240 g, power became 1711.62 W with 2.48 g/W efficiency, and 12179 [rpm] revolution for 22.2 V voltage and 77.1 A current, respectively. The 5 different analyses are performed in the range of 2.9-12 million elements, and the solution meshes with the lowest number of elements by performing parametric studies with the ANSYS program that gives the most accurate result.