The heat transfer, friction factor, pressure difference, Nusselt number of a helical coil tube using variable pressure and velocity during inlet for various values of Dean number [ratio of coil diameter (D) to tube diameter (d)] has been studied using commercially available computational tool. A validation is performed using the computational tool through the experimental data and it was observed that the results are in good agreement. The helical coil of 0.3 m diame ter with four (4) turns of inner diameter 0.01 m with length 3.77 has been modelled, meshed and analyzed for both laminar and turbulent flows of constant wall temperature and heat flux. A grid independence test is also performed. The results show that incr ease in Dean number increases the heat transfer of the helical tube. The increases in pressure have less effect on heat transfer during laminar flow while adverse effect can be observed during turbulent flow.